Product Name :
NDUFS3 Recombinant Rabbit Monoclonal Antibody [JU10-32]
Predicted band size :
20 kDa
Observed band size :
25 kDa
Synonyms:
CI 30 antibody CI 30KD antibody CI-30kD antibody Complex I 30KD antibody Complex I 30kDa subunit antibody COMPLEX I, MITOCHONDRIAL RESPIRATORY CHAIN, 30-KD SUBUNIT antibody Complex I-30kD antibody mitochondrial antibody NADH coenzyme Q reductase antibody NADH dehydrogenase (ubiquinone) Fe S protein 3 30kDa antibody 展开
Function :
NDUFS3 (NADH dehydrogenase ubiquinone iron-sulfur protein 3) is one of about 45 subunits comprising complex I of the oxidative phosphorylation electron transport chain. The multisubunit NADH: ubiquinone oxidoreductase (complex I) is the first enzyme complex in the electron transport chain of the mitochondria. NDUFS3 is the last subunit of the seven subunits that make up the core of complex I. Through use of chaotropic agents, complex I can be separated into three different fractions: a flavoprotein fraction, an iron-sulfur protein (IP) fraction, and a hydrophobic protein (HP) fraction. The IP fraction includes NDUFS1-7. NDUFS3 contains a highly conserved casein kinase II phosphorylation site. Mutations in the NDUFS3 gene may cause optic atrophy, Leigh syndrome and complex I deficiency.BuyAnthracen-2-ol
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human NDUFS3 aa 215-264 / 264.14590-52-4 uses
Species reactivity:
Human
Verify application:
WB, IHC-P, IF-Cell, IF-Tissue, IP
Coupling :
unconjugated
Clone number:
JU10-32
RRID:
AB_3070633
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33650031 Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 30 kDa
Positive control :
HepG2 lysates, MCF-7, human colon carcinoma tissue, human kidney tissue.