Cebo-treated subjects within the diagnostic group. Atomoxetine versus placebo p worth. c ADHD + D (atomoxetine) versus dyslexia-only (atomoxetine) p value. d ADHD + D (atomoxetine) versus ADHD-only (atomoxetine) p value. Intra-group p values: *p 0.05; **p 0.01; ***p 0.001; p values from t tests on LSMean transform. A, atomoxetine; ADHD, attention deficit/hyperactivity disorder; ADHDRS-IV-Parent:Inv, ADHD Rating Scale-IV-Parent-Version:Investigator-Administered and Scored; ADHDRS-IV-Teacher Version, ADHD Rating Scale-IV-Teacher-Version; K-SCT, Kiddie-Sluggish Cognitive Tempo; Hyp/Imp, Hyperactive/Impulsive; LSMean, least squares mean; P, placebo; Tx, treatment.b610 Table 2. Efficacy Results–Week 32 ADHD + D Measure n Baseline LSMean (mean) alter Dyslexia-only n Baseline LSMean (imply) alter ADHD-only n Baseline 21 21 21 9 9 9 21 9 21 34.95 22.38 12.57 21.00 13.00 eight.00 21.03 17.00 19.WIETECHA ET AL.LSMean (mean) changepapbADHDRS-IV-Parent Version: Inv (no adjustment for baseline score) Total 45 37.19715-49-2 Price 18 – 21.165894-07-5 Purity 59*** ( – 23.64) 18 15.00 – 5.68 ( – eight.61) Inattentive 45 22.42 – 13.84*** ( – 12.92) 18 ten.28 – four.14* ( – 5.67) Hyp/Imp 45 14.76 – eight.67*** ( – 9.80) 18 four.72 – 1.54 ( – 2.94) ADHDRS-IV-Teacher Version (no adjustment for baseline score) Total 23 23.97 – 9.05** ( – six.15) 11 15.55 – 6.88 ( – six.76) Inattentive 23 16.02 – five.19* ( – 4.28) 11 10.27 – three.65 ( – four.03) Hyp/Imp 23 7.96 – 3.86** ( – 1.87) 11 5.27 – three.23 ( – 2.73) K-SCT Interview (adjusted for baseline score) Parent 45 22.09 – 9.97*** ( – 10.40) 18 eight.12 – 14.67***( – 3.68) Teacher 23 22.87 – 7.56** ( – 7.00) 11 14.49 – 11.53* ( – 5.40) Youth 45 18.71 – four.96** ( – four.36) 18 14.61 – four.17 ( – 2.00)a b- 19.57*** ( – 22.62) 0.001 0.453 – 12.12*** ( – 14.33) 0.001 0.659 – 7.45*** ( – eight.29) 0.001 0.443 – eight.39 ( – 7.08) – 3.96 ( – four.19) – 4.43* ( – 2.89) – ten.50*** ( – ten.83) – 10.62* ( – 7.89) – 4.78** ( – 5.43) 0.903 0.875 0.713 0.707 0.695 0.752 0.038 0.812 0.455 0.547 0.921 0.ADHD + D (atomoxetine) versus Dyslexia-only (atomoxetine) p value. ADHD + D (atomoxetine) versus ADHD-only (atomoxetine) p value. Intra-group p values: *p 0.05; **p 0.01; ***p 0.001; p values from t tests on LSMean modify. ADHD, interest deficit/hyperactivity disorder; ADHDRS-IV-Parent:Inv, ADHD Rating Scale-IV-Parent-Version:Investigator-Administered and Scored; ADHDRS-IV-Teacher Version, ADHD Rating Scale-IV-Teacher-Version; K-SCT, Kiddie-Sluggish Cognitive Tempo; Hyp/Imp, Hyperactive/ Impulsive; LSMean, least squares imply.PMID:23439434 Improvements on the ADHDRS-IV-Teacher-Version Total score, and Inattentive and Hyperactive/Impulsive subscales, through extension phase treatment with atomoxetine, have been significant for subjects with ADHD + D, when analyzed with an adjustment for baseline scores; subjects with dyslexia-only showed considerable improvements around the Total score and Inattentive subscale score, although subjects with ADHD-only showed important improvements on the Hyperactive/Impulsive subscale score (Supplementary Table 2). When information were not adjusted for baseline scores, only subjects with ADHD + D showed significant improvements for the duration of remedy with atomoxetine on the ADHDRS-IV-Teacher-Version Total score and Inattentive subscale score, and subjects with ADHD-only showed substantial improvements in the course of treatment with atomoxetine on the Hyperactive/Impulsive subscale score (Table 2). Modifications from baseline on LPS throughout extension phase treatment with atomoxetine had been substantial for subjects with ADHD + D for the.